Diabetic Foot Ulcers (DFUs) are open sores or wounds that develop on the feet of people with diabetes. They commonly occur on areas exposed to repeated pressure or friction, such as the sole, heel, and toes. DFUs can vary in size, depth, location, and severity and may take longer to heal than typical wounds.

Diabetic Foot Ulcers are commonly associated with diabetic neuropathy and reduced blood circulation. Neuropathy is reduced sensation in the feet, making pain, pressure, temperature changes, and minor injuries less noticeable. Changes in foot structure can also create areas of increased pressure, while reduced blood flow can limit the oxygen and nutrients reaching damaged tissue. All of these factors combined can cause Diabetic Foot Ulcers to heal more slowly than regular wounds.

Diabetes can also affect the processes involved in wound healing. Elevated blood glucose can contribute to oxidative stress and persistent inflammation and can interfere with collagen formation, new blood-vessel growth, and immune-cell activity. When the skin is broken, microorganisms can enter the wound and cause infection, which may extend into deeper tissues, including bone.

Disclaimer: This information is for general educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Consult a qualified healthcare professional for advice about a wound or any health concern.