How cold atmospheric plasma (CAP)supports natural wound healing
Plasma is the fourth state of matter, next to solid, liquid and gas. It is created when energy is added to a gas, causing it to ionize and form reactive oxygen and nitrogen species, ions, free radicals and electric fields. These components can interact with biological tissue and influence cellular behavior.
In wound healing, the cold plasma cocktail disrupts biofilm, kills bacteria, stimulates the growth and migration of skin cells, and improves microcirculation up to several millimeters deep. Together this creates a biological environment that supports faster wound closure.
PLASOMA empowers medical professionals to deliver their best possible care
Close more wounds
Close wounds faster
High quality wound closure
Enhance wound healing predictability
Cold atmospheric plasma for wound healing
Plasma medicine is a rapidly developing field that applies cold atmospheric plasma to the human body. “Cold” refers to the fact that the plasma temperature remains close to body temperature, making it safe for use on living tissue. “Atmospheric” means that the plasma is produced at the pressure of ambient air.
Cold plasma has long been used in industry for cleaning and sterilizing surfaces and medical instruments. In healthcare, it is now used to stimulate tissue regeneration, promote wound healing and fight infection. When plasma comes into contact with the wound, a cocktail of reactive species such as ozone, nitric oxide and hydrogen peroxide, together with an electric field, help reduce bacterial load and activate cells responsible for tissue repair.
Dual Plasma technology explained
PLASOMA uniquely delivers cold plasma directly in the wound in combination with electrostimulation. That combination we call ‘Dual Plasma‘. Between the plasma pad and the wound, the entire space is filled with cold plasma inside a closed system. This ensures that all reactive species, including the short-lived ones such as nitric oxide, and the electric field can act directly on the wound.
Because the plasma is generated in a closed system, these reactive species remain where they are most effective, inside the wound area, without escaping into the surrounding air. At the same time, a defined electric current runs through the wound area. This current and associated electric field work as a gentle electrostimulation, which is linked to improvement in microcirculation (local blood supply), angiogenesis and activation of deeper tissue repair processes.
How cold plasma supports the wound healing process
Cold atmospheric plasma therapy offers several scientifically proven benefits for wound healing including:
- Disruption of biofilm
- Efficient killing of bacteria, including antibiotic-resistant species, for infection prevention or resolution
- Stimulation of skin cells and immune cells for faster tissue repair and reduction of inflammation
- Improvement of microcirculation for better oxygen and nutrient delivery
These effects make plasma wound care highly effective for complex wounds.
Clinical evidence: Demonstrated results in complex wound healing
PLASOMA is shown to close 62% of complex wounds. That is 2.5x more than standard wound care. PLASOMA empowers medical professionals to deliver their best possible care. These clinical wound healing results, supported by case series from real-world practice, demonstrate the impact of cold plasma therapy on improved healing outcomes for complex wounds.
